BIOVIA Pipeline Pilot 2024 v24.1.0.334 x64 + Discovery Studio

Published on: 2024-04-08 11:01:13

Categories: 12

Description

BIOVIA Discovery Studio is the original version of BIOVIA for the science of prophecy, modeling and simulation in the life sciences. BIOVIA Discovery Studio includes the highly efficient CHARMm molecular mechanics simulator. With over 30 years of rigorous academic research, CHARMm has been developed with a primary focus on study proteins, peptides, small molecule ligands, nucleic acids, lipids and carbohydrates. For quantum mechanics based studies, this software includes the DMol3 program. DMol3 is a DFT program with a long record of successful business applications. DMol3, using its unique approach to solving quantum mechanical equations, is one of the fastest ways to do calculations, an advantage that is particularly evident for larger systems with more than 500 atoms.

Features and features of the BIOVIA Discovery Studio suite:

Molecular Mechanics (MM) calculations using CHARMm c41b1
Supports a wide range of power fields, including CGenFF, charmm36, charmm27, charmm22, CHARMm, CHARMm-polarH, CFF, MMFF and more
Full support for CHARMM partition mechanism and support for invalid custom definition
Rapid and precise ionization of residual protein and pKs using the Born CHARMm (GB) solvent model
Fast method of drinking water solvent with optional anti-ions suitable for very large molecular systems
Perform any explicit solvent or minimize solvent-based molecular mechanics (MM) based on GB
Perform an explicit solvent or solvent-based molecular dynamics simulation
Add an implicit membrane to the protein structure to formulate simulation models based on field strength
Use CDOCKER, a CHARMm-based docking engine to perform ligand-based flexible bonding and docking refinement.

required system

Operating System
OS: Windows 10 / Windows Server 2019 / Windows Server 2016
CPU: Intel-compatible x86_64 architecture
RAM: 4 GB per core
Space: 70 to 80 GB

Pictures

studio

Installation guide

Listed in Readme file.

For version 3 As mentioned in the Readme file, the modules are installed according to the selected license.

Note: In the Pipeline Pilot 2024, the Discovery collection package (Discovery server) is not available.

2024 v24.1.0.334 installation: If you encounter server error after installation, first go to “C:\Program Files\BIOVIA\PPS\install” and create a folder called disk1. Then Copy the “apache2common.dll” file from the path:
C:\Program Files\BIOVIA\PPS\apps\scitegic\websvc\bin\win64 to path “C:\Program Files\BIOVIA\PPS\bin”. Run the scitegicsetup.exe from the bin folder. Select the Reinstall/Repair option. In the module section, tick each one you need and click Next to start the installation. After starting the installation, enter the “C:\Program Files\BIOVIA\PPS\apps\scitegic\core\bin\win64” folder, when the “lpl.dll” file is created, copy the lpl.dll file in the crack folder and replace it. After the installation is completed, the following message will appear in the opened window (according to the picture above):

Your Apache service name is: BIOVIA Pipeline Pilot 24.1.0 Service (Httpd)

Click Next, then the page will open in the browser, which will show you the default user and password (scitegicadmin), use it to enter the server and also the software.
If you are asked for server details after running the software. Place localhost in front of the ports (according to the picture above)

The 2016 version was installed and successfully activated on November 25, 96 in Windows 10 64-bit.

The 2024 v24.1.0.334 was installed and successfully activated on Decumber 27, 2023 in Windows 10 64-bit.